Stabilin 2 (STAB2) (AA 1550-1850) anticorps

N° du produit ABIN7170685

Détail du produit

Antigène: Stabilin 2 (STAB2)

Épitope: AA 1550-1850

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Stabilin-2 protein (1550-1850AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Stabilin 2 (STAB2)

Autre désignation: STAB2 (STAB2 Produits)

Synonymes: anticorps FEEL2, anticorps FELE-2, anticorps FELL2, anticorps FEX2, anticorps HARE, anticorps si:dkey-207j16.6, anticorps FEEL-2, anticorps FELL, anticorps MFEEL-2, anticorps STAB-2, anticorps Hare, anticorps hare, anticorps stabilin 2, anticorps stabilin-2, anticorps STAB2, anticorps stab2, anticorps LOC100181366, anticorps Stab2

Sujet:

Background: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.

Aliases: 190 kDa form stabilin-2 antibody, 190 kDa hyaluronan receptor for endocytosis antibody, EGF-like antibody, FAS1 EGF-like and X-link domain-containing adhesion molecule 2 antibody, Fasciclin antibody, FEEL-2 antibody, FEEL2 antibody, FELL antibody, FEX2 antibody, HARE antibody, Hyaluronan receptor for endocytosis antibody, laminin-type EGF-like and link domain-containing scavenger receptor 2 antibody, link domain-containing scavenger receptor 2 antibody, STAB-2 antibody, Stab2 antibody, STAB2_HUMAN antibody

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process