STAMBP anticorps (AA 1-424) (Biotin)

N° du produit ABIN7170687

L’anticorps Lapin Polyclonal anti-STAMBP a été validé pour ELISA. Il convient pour détecter STAMBP dans des échantillons de Humain.

Aperçu rapide pour STAMBP anticorps (AA 1-424) (Biotin) (ABIN7170687)

Antigène: STAMBP (STAM Binding Protein (STAMBP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAMBP est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-STAMBP anticorps (Biotin)

Épitope: AA 1-424

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human STAM-binding protein (1-424AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur STAMBP

Antigène: STAMBP (STAM Binding Protein (STAMBP))

Autre désignation: STAMBP

Sujet:

Background: Zinc metalloprotease that specifically cleaves \'Lys-63\'-linked polyubiquitin chains. Does not cleave \'Lys-48\'-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization .Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.

Aliases: AMSH antibody, Associated molecule with the SH3 domain of STAM antibody, Endosome associated ubiquitin isopeptidase antibody, Endosome-associated ubiquitin isopeptidase antibody, MGC126516 antibody, MGC126518 antibody, MICCAP antibody, STABP_HUMAN antibody, STAM binding protein antibody, STAM-binding protein antibody, Stambp antibody

UniProt: O95630