TTI1 anticorps (AA 692-858) (Biotin)
Aperçu rapide pour TTI1 anticorps (AA 692-858) (Biotin) (ABIN7171702)
Antigène
Voir toutes TTI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 692-858
-
Réactivité croisée
- Humain
-
Purification
- >95%, Protein G purified
-
Immunogène
- Recombinant Human TELO2-interacting protein 1 homolog protein (692-858AA)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- TTI1 (TELO2 Interacting Protein 1 (TTI1))
-
Autre désignation
- TTI1
-
Sujet
-
Background: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
Aliases: TTI1 antibody, KIAA0406 antibody, SMG10 antibody, TELO2-interacting protein 1 homolog antibody, Protein SMG10 antibody
-
UniProt
- O43156
Antigène
-