E2F6 anticorps (AA 1-281)

N° du produit ABIN7172529

L’anticorps Lapin Polyclonal anti-E2F6 a été validé pour IHC et ELISA. Il convient pour détecter E2F6 dans des échantillons de Humain.

Aperçu rapide pour E2F6 anticorps (AA 1-281) (ABIN7172529)

Antigène: E2F6 (E2F Transcription Factor 6 (E2F6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F6 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-E2F6 anticorps

Épitope: AA 1-281

Fonction: E2F6 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Transcription factor E2F6 protein (1-281AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur E2F6

Antigène: E2F6 (E2F Transcription Factor 6 (E2F6))

Autre désignation: E2F6

Sujet:

Background: Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5\\\'-TTTC[CG]CGC-3\\\'. Has a preference for the 5\\\'-TTTCCCGC-3\\\' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.

Aliases: E2F 6 antibody, E2F binding site modulating activity protein antibody, E2F transcription factor 6 antibody, E2F transcription factor 6 isoform 1 antibody, E2F-6 antibody, E2F6 antibody, E2F6_HUMAN antibody, EMA antibody, MGC111545 antibody, Transcription factor E2F6 antibody

UniProt: O75461