P4HTM anticorps (AA 82-563)

N° du produit ABIN7172999

Cet anticorps Lapin Polyclonal détecte spécifiquement P4HTM dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour P4HTM anticorps (AA 82-563) (ABIN7172999)

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P4HTM est non-conjugé

Application: ELISA

Détail du produit anti-P4HTM anticorps

Épitope: AA 82-563

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Transmembrane prolyl 4-hydroxylase protein (82-563AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur P4HTM

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Autre désignation: P4HTM

Sujet:

Background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at \'Pro-402\' and \'Pro-564\'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Aliases: EGLN4 antibody, HIF PH4 antibody, HIF Prolyl Hydroxylase 4 antibody, HIF prolyl hydroxylase PH 4 antibody, HIF prolyl hydroxylase PH4 antibody, HIF-PH4 antibody, HIF-prolyl hydroxylase 4 antibody, HIFPH4 antibody, HPH 4 antibody, HPH-4 antibody, Hypoxia inducible factor prolyl 4 hydroxylase antibody, Hypoxia-inducible factor prolyl hydroxylase 4 antibody, P4H with transmembrane domain antibody, P4H-TM antibody, P4htm antibody, P4HTM_HUMAN antibody, PH 4 antibody, PH4 antibody, PHD 4 antibody, Proline 4 hydroxylase antibody, prolyl 4-hydroxylase antibody, Transmembrane prolyl 4-hydroxylase antibody

UniProt: Q9NXG6