TMEM59 anticorps (AA 59-201) (FITC)

N° du produit ABIN7173247

Cet anticorps anti-TMEM59 est un anticorps Lapin Polyclonal détectant TMEM59 dans . Adapté pour Humain.

Aperçu rapide pour TMEM59 anticorps (AA 59-201) (FITC) (ABIN7173247)

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM59 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-TMEM59 anticorps (FITC)

Épitope: AA 59-201

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Transmembrane protein 59 protein (59-201AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TMEM59

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Autre désignation: TMEM59

Sujet:

Background: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy (PubMed:27273576, PubMed:23376921). Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP (PubMed:20427278). Inhibits APP transport to the cell surface and further shedding (PubMed:20427278).

Aliases: C1orf8 antibody, HSPC001 antibody, Liver membrane-bound protein antibody, TMEM59 antibody, TMEM59 transmembrane protein 59 antibody, TMM59_HUMAN antibody, Transmembrane protein 59 antibody

UniProt: Q9BXS4