TGS1 anticorps (AA 714-853)

N° du produit ABIN7173394

Cet anticorps anti-TGS1 est un anticorps Lapin Polyclonal détectant TGS1 dans ELISA, WB et IHC. Adapté pour Humain.

Aperçu rapide pour TGS1 anticorps (AA 714-853) (ABIN7173394)

Antigène: TGS1 (Trimethylguanosine Synthase 1 (TGS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGS1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TGS1 anticorps

Épitope: AA 714-853

Fonction: TGS1 Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Trimethylguanosine synthase protein (714-853AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TGS1

Antigène: TGS1 (Trimethylguanosine Synthase 1 (TGS1))

Autre désignation: TGS1

Sujet:

Background: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.

Aliases: Cap specific guanine N2 methyltransferase antibody, Cap-specific guanine-N2 methyltransferase antibody, CLL associated antigen KW 2 antibody, CLL-associated antigen KW-2 antibody, DKFZp762A163 antibody, FLJ22995 antibody, HCA137 antibody, Hepatocellular carcinoma associated antigen 137 antibody, Hepatocellular carcinoma-associated antigen 137 antibody, NCOA6IP antibody, Nuclear receptor coactivator 6 interacting protein antibody, Nuclear receptor coactivator 6-interacting protein antibody, PIMT antibody, PIPMT antibody, PRIP interacting protein PIPMT antibody, PRIP interacting protein with methyltransferase domain antibody, PRIP interacting protein with methyltransferase motif antibody, PRIP-interacting protein with methyltransferase motif antibody, SEREX defined antibody, TGS 1 antibody, Tgs1 antibody, TGS1_HUMAN antibody, Trimethylguanosine synthase antibody, Trimethylguanosine synthase homolog (S. cerevisiae) antibody, Trimethylguanosine synthase homolog antibody

UniProt: Q96RS0

Pathways: Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization