TSEN15 anticorps (AA 1-171) (HRP)

N° du produit ABIN7173539

Détail du produit anti-TSEN15 anticorps (HRP)

Antigène: TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

Épitope: AA 1-171

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSEN15 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human tRNA-splicing endonuclease subunit Sen15 protein (1-171AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TSEN15

Antigène: TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

Autre désignation: TSEN15 (TSEN15 Produits)

Synonymes: anticorps 5730449L18Rik, anticorps AL023077, anticorps Sen15, anticorps C1orf19, anticorps sen15, anticorps tRNA splicing endonuclease subunit 15, anticorps Tsen15, anticorps TSEN15

Sujet:

Background: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5\' and 3\' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2\',3\' cyclic phosphate and 5\'-OH termini (PubMed:15109492, PubMed:27392077). There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3\'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3\'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (PubMed:15109492).

Aliases: TSEN15 antibody, C1orf19 antibody, SEN15 antibody, tRNA-splicing endonuclease subunit Sen15 antibody, SEN15 homolog antibody, HsSEN15 antibody, tRNA-intron endonuclease Sen15 antibody

UniProt: Q8WW01