UFD1L anticorps (AA 1-307)
Aperçu rapide pour UFD1L anticorps (AA 1-307) (ABIN7174388)
Antigène
Voir toutes UFD1L AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 1-307
-
Fonction
- UFD1 Antibody
-
Purification
- Antigen Affinity Purified
-
Immunogène
- Recombinant Human Ubiquitin recognition factor in ER-associated degradation protein 1 protein (1-307AA)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
-
Autre désignation
- UFD1
-
Sujet
-
Background: Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.
Aliases: UB fusion protein 1 antibody, Ubiquitin fusion degradation 1 like (yeast) antibody, Ubiquitin fusion degradation 1 like antibody, Ubiquitin fusion degradation protein 1 homolog antibody, UFD1 antibody, UFD1_HUMAN antibody, UFD1L antibody
-
UniProt
- Q92890
Antigène
-