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UBASH3A anticorps (AA 287-455)

L’anticorps Lapin Polyclonal anti-UBASH3A a été validé pour ELISA, WB et IF. Il convient pour détecter UBASH3A dans des échantillons de Humain.
N° du produit ABIN7174413

Aperçu rapide pour UBASH3A anticorps (AA 287-455) (ABIN7174413)

Antigène

Voir toutes UBASH3A Anticorps
UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Reactivité

  • 30
  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 31
  • 4
  • 2
Lapin

Clonalité

  • 34
  • 3
Polyclonal

Conjugué

  • 22
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp UBASH3A est non-conjugé

Application

  • 24
  • 19
  • 3
  • 3
  • 3
  • 2
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (IF)
  • Épitope

    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 287-455

     Réactivité croisée

    Humain

    Purification

    >95%, Protein G purified

    Immunogène

    Recombinant Human Ubiquitin-associated and SH3 domain-containing protein A protein (287-455AA)

    Isotype

    IgG
  • Indications d'application

    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène

    UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

    Autre désignation

    UBASH3A

    Sujet

    Background: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH . May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.

    Aliases: Cbl interacting protein 4 antibody, Cbl-interacting protein 4 antibody, CLIP4 antibody, STS 2 antibody, STS-2 antibody, Suppressor of T cell receptor signaling 2 antibody, Suppressor of T-cell receptor signaling 2 antibody, T cell ubiquitin ligand antibody, T cell ubiquitin ligand protein antibody, T-cell ubiquitin ligand 1 antibody, TULA antibody, TULA-1 antibody, UBASH3A antibody, ubiquitin associated and SH3 domain containing, A antibody, Ubiquitin-associated and SH3 domain-containing protein A antibody, UBS3A_HUMAN antibody

    UniProt

    P57075
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