MYO1G anticorps (AA 209-389)
Aperçu rapide pour MYO1G anticorps (AA 209-389) (ABIN7174949)
Antigène
Voir toutes MYO1G AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 209-389
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Fonction
- MYO1G Antibody
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Unconventional myosin-Ig protein (209-389AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MYO1G (Myosin IG (MYO1G))
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Autre désignation
- MYO1G
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Sujet
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Background: Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis.
Aliases: mHag HA-2 antibody, Minor histocompatibility antigen HA-2 antibody, Myo1g antibody, MYO1G_HUMAN antibody, myosin IG antibody
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UniProt
- B0I1T2
Antigène
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