Myosin XVIIIA anticorps (AA 1849-2054) (HRP)

N° du produit ABIN7174984

Cet anticorps anti-Myosin XVIIIA est un anticorps Lapin Polyclonal détectant Myosin XVIIIA dans ELISA. Adapté pour Humain.

Aperçu rapide pour Myosin XVIIIA anticorps (AA 1849-2054) (HRP) (ABIN7174984)

Antigène: Myosin XVIIIA (MYO18A)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myosin XVIIIA est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-Myosin XVIIIA anticorps (HRP)

Épitope: AA 1849-2054

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Unconventional myosin-XVIIIa protein (1849-2054AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Myosin XVIIIA

Antigène: Myosin XVIIIA (MYO18A)

Autre désignation: MYO18A

Sujet:

Background: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).

Aliases: MYO18A antibody, CD245 antibody, KIAA0216 antibody, MYSPDZ antibody, Unconventional myosin-XVIIIa antibody, Molecule associated with JAK3 N-terminus antibody, MAJN antibody, Myosin containing a PDZ domain antibody, Surfactant protein receptor SP-R210 antibody, SP-R210 antibody

UniProt: Q92614