VPS29 anticorps (AA 68-145) (FITC)

N° du produit ABIN7175306

Cet anticorps Lapin Polyclonal détecte spécifiquement VPS29 dans . Il présente une réactivité envers Humain.

Aperçu rapide pour VPS29 anticorps (AA 68-145) (FITC) (ABIN7175306)

Antigène: VPS29 (Vacuolar Protein Sorting 29 (VPS29))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS29 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-VPS29 anticorps (FITC)

Épitope: AA 68-145

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Vacuolar protein sorting-associated protein 29 protein (68-145AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur VPS29

Antigène: VPS29 (Vacuolar Protein Sorting 29 (VPS29))

Autre désignation: VPS29

Sujet:

Background: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA) (Probable). Involved in GLUT1 endosome-to-plasma membrane trafficking, the function is dependent of association with ANKRD27 (PubMed:24856514).

Aliases: DC15 antibody, DC7 antibody, DKFZp564F0223 antibody, FLJ20492 antibody, hVPS29 antibody, PEP11 antibody, PEP11 homolog antibody, Retromer protein antibody, Vacuolar protein sorting 29 antibody, Vacuolar protein sorting 29 (yeast homolog) antibody, Vacuolar protein sorting 29 (yeast) antibody, Vacuolar protein sorting 29 homolog (S. cerevisiae) antibody, Vacuolar protein sorting 29 homolog antibody, Vacuolar protein sorting associated protein 29 antibody, Vacuolar protein sorting-associated protein 29 antibody, Vacuolar sorting protein VPS29/PEP11 antibody, Vesicle protein sorting 29 antibody, VPS 29 antibody, VPS29 antibody, VPS29 retromer complex component antibody, VPS29_HUMAN antibody, x 007 protein antibody

UniProt: Q9UBQ0