SNF8 anticorps (AA 1-258) (FITC)

N° du produit ABIN7175342

Cet anticorps Lapin Polyclonal détecte spécifiquement SNF8 dans . Il présente une réactivité envers Humain.

Aperçu rapide pour SNF8 anticorps (AA 1-258) (FITC) (ABIN7175342)

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNF8 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-SNF8 anticorps (FITC)

Épitope: AA 1-258

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Vacuolar-sorting protein SNF8 protein (1-258AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SNF8

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Autre désignation: SNF8

Sujet:

Background: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Aliases: Dot3 antibody, ELL associated protein of 30 kDa antibody, ELL-associated protein of 30 kDa antibody, ESCRT-II complex subunit VPS22 antibody, hVps22 antibody, snf8 antibody, SNF8 ESCRTII complex subunit homolog (S cerevisiae) antibody, SNF8_HUMAN antibody, Vacuolar sorting protein SNF8 antibody, Vacuolar-sorting protein SNF8 antibody, VPS22 antibody

UniProt: Q96H20