HSD17B12 anticorps (AA 40-181) (HRP)

N° du produit ABIN7175452

Cet anticorps anti-HSD17B12 est un anticorps Lapin Polyclonal détectant HSD17B12 dans ELISA. Adapté pour Humain.

Aperçu rapide pour HSD17B12 anticorps (AA 40-181) (HRP) (ABIN7175452)

Antigène: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B12 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-HSD17B12 anticorps (HRP)

Épitope: AA 40-181

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Very-long-chain 3-oxoacyl-CoA reductase protein (40-181AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HSD17B12

Antigène: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Autre désignation: HSD17B12

Sujet:

Background: Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.

Aliases: 12,3-ketoacyl-CoA reductase,short chain antibody, 17 beta HSD 12 antibody, 17 beta hydroxysteroid dehydrogenase 12 antibody, 17-@beta-HSD XII antibody, 17-@beta-hydroxysteroid dehydrogenase XII antibody, 17-beta-HSD 12 antibody, 17-beta-hydroxysteroid dehydrogenase 12 antibody, 17beta HSD type 12 antibody, 3 ketoacyl CoA reductase antibody, 3-ketoacyl-CoA reductase antibody, DHB12_HUMAN antibody, Estradiol 17 beta dehydrogenase 12 antibody, Estradiol 17-beta-dehydrogenase 12 antibody, HSD17B12 antibody, Hydroxysteroid (17-beta) dehydrogenase 12 antibody, KAR antibody, KIK-I antibody, Kik1 antibody, SDR12C1 antibody, Short chain dehydrogenase/reductase family 12C member 1 antibody, Steroid dehydrogenase homolog antibody

UniProt: Q53GQ0

Pathways: Steroid Hormone Biosynthesis