Villin 1 anticorps (AA 1-350)
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- Antigène Voir toutes Villin 1 (VIL1) Anticorps
- Villin 1 (VIL1)
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Épitope
- AA 1-350
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Villin 1 est non-conjugé
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Application
- Immunohistochemistry (IHC), ELISA
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Villin-1 protein (1-350AA)
- Isotype
- IgG
- Top Product
- Discover our top product VIL1 Anticorps primaire
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anti-Villin 1 (VIL1) (AA 1-320) antibody
VIL1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Villin 1 (VIL1) (AA 180-207), (N-Term) antibodyVIL1 Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB17824 unconjugated
anti-Villin 1 (VIL1) (AA 1-209) antibodyVIL1 Reactivité: Humain WB, IHC, FACS, ELISA, ICC Hôte: Souris Monoclonal 3E5G11 unconjugated
anti-Villin 1 (VIL1) (N-Term) antibodyVIL1 Reactivité: Humain WB, IF, IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Villin 1 (VIL1) (AA 1-209) antibodyVIL1 Reactivité: Humain WB, IHC, ELISA Hôte: Souris Monoclonal 5E3B2 unconjugated
anti-Villin 1 (VIL1) (AA 1-421) antibodyVIL1 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Villin 1 (VIL1) (AA 179-311) antibodyVIL1 Reactivité: Humain WB, IHC, StM Hôte: Souris Monoclonal VIL1-1314 unconjugated
anti-Villin 1 (VIL1) (AA 179-311) antibodyVIL1 Reactivité: Humain IHC, StM Hôte: Souris Monoclonal rVIL1-1325 unconjugated Recombinant Antibody
anti-Villin 1 (VIL1) (AA 1-421) antibodyVIL1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2F10 unconjugated
anti-Villin 1 (VIL1) (AA 600-700) antibodyVIL1 Reactivité: Humain IHC Hôte: Lapin Monoclonal MSVA-459R unconjugated Recombinant Antibody
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- Villin 1 (VIL1)
- Autre désignation
- VIL1 (VIL1 Produits)
- Synonymes
- anticorps D2S1471, anticorps VIL, anticorps Vil, anticorps vil1, anticorps MGC64339, anticorps VIL1, anticorps vil1l, anticorps zgc:55779, anticorps villin 1, anticorps villin 1 S homeolog, anticorps VIL1, anticorps Vil1, anticorps vil1.S, anticorps vil1
- Sujet
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Background: Epithelial cell-specific Ca2+-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA), binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis. Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium. Appears to regulate cell death by maintaining mitochondrial integrity. Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair. Upon S.flexneri cell infection, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination.
Aliases: D2S1471 antibody, OTTHUMP00000164145 antibody, VIL antibody, VIL1 antibody, VILI_HUMAN antibody, Villin 1 antibody, Villin-1 antibody, Villin1 antibody
- UniProt
- P09327
- Pathways
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
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