WDFY2 anticorps (AA 2-114)

N° du produit ABIN7175695

Détail du produit anti-WDFY2 anticorps

Antigène: WDFY2 (ZFYVE22) (Zinc Finger, FYVE Domain Containing 22 (ZFYVE22))

Épitope: AA 2-114

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDFY2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human WD repeat and FYVE domain-containing protein 2 protein (2-114AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur WDFY2

Antigène: WDFY2 (ZFYVE22) (Zinc Finger, FYVE Domain Containing 22 (ZFYVE22))

Autre désignation: WDFY2 (ZFYVE22 Produits)

Synonymes: anticorps PROF, anticorps RP11-147H23.1, anticorps WDF2, anticorps ZFYVE22, anticorps 5830485M08, anticorps B130024L21Rik, anticorps ProF, anticorps WD repeat and FYVE domain-containing protein 2, anticorps WD repeat and FYVE domain containing 2, anticorps wdfy-2, anticorps WDFY2, anticorps Wdfy2

Sujet:

Background: Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 (PubMed:17313651). Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 (PubMed:18388859). Plays a role in endosomal control of AKT2 signaling, required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates (By similarity). Participates in transferrin receptor endocytosis (PubMed:16873553).

Aliases: PROF antibody, Propeller-FYVE protein antibody, RP11 147H23.1 antibody, WD repeat and FYVE domain containing 2 antibody, WD repeat and FYVE domain-containing protein 2 antibody, WD40 and FYVE domain containing 2 antibody, WD40- and FYVE domain-containing protein 2 antibody, WDF2 antibody, Wdfy2 antibody, WDFY2_HUMAN antibody, ZFYVE22 antibody, Zinc finger FYVE domain-containing protein 22 antibody

UniProt: Q96P53