WDFY3 anticorps (AA 1-100)

N° du produit ABIN7175699

Cet anticorps Lapin Polyclonal détecte spécifiquement WDFY3 dans ELISA, IF et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour WDFY3 anticorps (AA 1-100) (ABIN7175699)

Antigène: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDFY3 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-WDFY3 anticorps

Épitope: AA 1-100

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human WD repeat and FYVE domain-containing protein 3 protein (1-100AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur WDFY3

Antigène: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Autre désignation: WDFY3

Sujet:

Background: Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.

Aliases: WDFY3 antibody, KIAA0993 antibody, WD repeat and FYVE domain-containing protein 3 antibody, Autophagy-linked FYVE protein antibody, Alfy antibody

UniProt: Q8IZQ1