MORG1 anticorps (AA 64-315) (FITC)
Aperçu rapide pour MORG1 anticorps (AA 64-315) (FITC) (ABIN7175712)
Antigène
Voir toutes MORG1 (wdr83) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 64-315
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human WD repeat domain-containing protein 83 protein (64-315AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
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Autre désignation
- WDR83
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Sujet
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Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.
Aliases: MAPK organizer 1 antibody, MGC4238 antibody, Mitogen activated protein kinase organizer 1 antibody, Mitogen-activated protein kinase organizer 1 antibody, MORG 1 antibody, WD repeat domain-containing protein 83 antibody, wdr83 antibody, WDR83_HUMAN antibody
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UniProt
- Q9BRX9
Antigène
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