GLIS2 anticorps (AA 332-505)

N° du produit ABIN7176582

Détail du produit anti-GLIS2 anticorps

Antigène: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Épitope: AA 332-505

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLIS2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Zinc finger protein GLIS2 protein (332-505AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GLIS2

Antigène: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Autre désignation: GLIS2 (GLIS2 Produits)

Synonymes: anticorps glis2b, anticorps nkl-A, anticorps xNKLb, anticorps NKL, anticorps NPHP7, anticorps Gli5, anticorps Klf16, anticorps Nkl, anticorps glis2a, anticorps nphp7, anticorps GLIS family zinc finger 2 L homeolog, anticorps GLIS family zinc finger 2, anticorps GLIS family zinc finger 2 S homeolog, anticorps glis2.L, anticorps GLIS2, anticorps Glis2, anticorps glis2.S

Sujet:

Background: Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway (By similarity). Represses the Hedgehog-dependent expression of Wnt4 (By similarity). Necessary to maintain the differentiated epithelial phenotype in renal cells through the inhibition of SNAI1, which itself induces the epithelial-to-mesenchymal transition (By similarity). Represses transcriptional activation mediated by CTNNB1 in the Wnt signaling pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation (By similarity).

Aliases: FLJ38247 antibody, GLI similar 2 antibody, GLI-similar 2 antibody, GLIS 2 antibody, GLIS family zinc finger 2 antibody, glis2 antibody, GLIS2_HUMAN antibody, Kruppel like zinc finger protein GLIS2 antibody, Neuronal Krueppel-like protein antibody, Zinc finger protein GLIS2 antibody

UniProt: Q9BZE0