Moloney Murine Leukemia Virus Gag (AA 216-478) anticorps

N° du produit ABIN7176872

Cet anticorps Lapin Polyclonal détecte spécifiquement dans ELISA. Il présente une réactivité envers Moloney Murine Leukemia Virus (MoMuLV).

Aperçu rapide pour Moloney Murine Leukemia Virus Gag (AA 216-478) anticorps (ABIN7176872)

Antigène: Moloney Murine Leukemia Virus Gag

Reactivité: Moloney Murine Leukemia Virus (MoMuLV)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA

Détail du produit

Épitope: AA 216-478

Fonction: gag Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Moloney Murine Leukemia Virus Gag

Sujet:

Background: Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.Matrix protein p15 targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex.Capsid protein p30 forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.Nucleocapsid protein p10 is involved in the packaging and encapsidation of two copies of the genome. Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5\\\'-end of the genome. This binding is dependent on genome dimerization.

Aliases: gag antibody, Gag polyprotein antibody, Pr65gag antibody, Core polyprotein) [Cleaved into: Matrix protein p15 antibody, MA), RNA-binding phosphoprotein p12 antibody, pp12), Capsid protein p30 antibody, CA), Nucleocapsid protein p10-Gag antibody, NC-gag)] antibody

UniProt: P03332