FAIM3 anticorps (AA 18-262)
Aperçu rapide pour FAIM3 anticorps (AA 18-262) (ABIN7177185)
Antigène
Voir toutes FAIM3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 18-262
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Réactivité croisée
- Souris, Rat
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: WB:1:1000-1:5000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
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Autre désignation
- Fcmr
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Sujet
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Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Aliases: Fcmr antibody, Faim3 antibody, TosoFas apoptotic inhibitory molecule 3 antibody, IgM Fc fragment receptor antibody, Regulator of Fas-induced apoptosis Toso antibody
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UniProt
- A1KXC4
Antigène
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