Cobra Venom Factor,CVF (AA 733-984) anticorps

N° du produit ABIN7178124

L’anticorps Lapin Polyclonal anti- a été validé pour ELISA et WB. Il convient pour détecter dans des échantillons de Cobra.

Aperçu rapide pour Cobra Venom Factor,CVF (AA 733-984) anticorps (ABIN7178124)

Antigène: Cobra Venom Factor,CVF

Reactivité: Cobra

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Détail du produit

Épitope: AA 733-984

Fonction: Cobra venom factor Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Naja kaouthia Cobra venom factor protein (733-984AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Cobra Venom Factor,CVF

Autre désignation: Cobra venom factor

Sujet:

Background: Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.

Aliases: antibody, Cobra venom factor antibody, CVF antibody, CVFk antibody, Complement C3 homolog) [Cleaved into: Cobra venom factor alpha chain, Cobra venom factor gamma chain, Cobra venom factor beta chain] antibody

UniProt: Q91132