Hepcidin anticorps

N° du produit ABIN7178664

L’anticorps Lapin Polyclonal anti-Hepcidin a été validé pour WB, IHC et ELISA. Il convient pour détecter Hepcidin dans des échantillons de Humain.

Aperçu rapide pour Hepcidin anticorps (ABIN7178664)

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hepcidin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Hepcidin anticorps

Fonction: HAMP Antibody

Réactivité croisée: Souris

Purification: Affinity purification

Immunogène: Recombinant protein of Human HAMP

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Hepcidin

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Autre désignation: HAMP

Sujet:

Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

Aliases: Hamp antibody, HEPC antibody, HEPC_HUMAN antibody, Hepc20 antibody, Hepc25 antibody, HEPCIDIN antibody, Hepcidin 20 antibody, Hepcidin 25 antibody, Hepcidin antimicrobial peptide antibody, Hepcidin-20 antibody, Hepcidin25 antibody, HFE2 antibody, HFE2B antibody, LEAP 1 antibody, LEAP-1 antibody, LEAP1 antibody, Liver expressed antimicrobial peptide antibody, Liver-expressed antimicrobial peptide 1 antibody, PLTR antibody, Putative liver tumor regressor antibody

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis