TIMP1 anticorps (AA 24-217) (Biotin)

N° du produit ABIN7178942

Cet anticorps Lapin Polyclonal détecte spécifiquement TIMP1 dans ELISA. Il présente une réactivité envers Rat.

Aperçu rapide pour TIMP1 anticorps (AA 24-217) (Biotin) (ABIN7178942)

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP1 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-TIMP1 anticorps (Biotin)

Épitope: AA 24-217

Fonction: Timp1 Antibody, Biotin conjugated

Réactivité croisée: Rat

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TIMP1

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Autre désignation: Timp1

Sujet:

Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells, procathepsin L is required for maximal activity.

Aliases: Timp1 antibody, Timp-1 antibody, Metalloproteinase inhibitor 1 antibody, Tissue inhibitor of metalloproteinases 1 antibody, TIMP-1 antibody

UniProt: P30120