TIMP1 anticorps (AA 24-217) (FITC)
Aperçu rapide pour TIMP1 anticorps (AA 24-217) (FITC) (ABIN7178943)
Antigène
Voir toutes TIMP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 24-217
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Fonction
- Timp1 Antibody, FITC conjugated
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Réactivité croisée
- Rat
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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Autre désignation
- Timp1
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Sujet
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Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells, procathepsin L is required for maximal activity.
Aliases: Timp1 antibody, Timp-1 antibody, Metalloproteinase inhibitor 1 antibody, Tissue inhibitor of metalloproteinases 1 antibody, TIMP-1 antibody
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UniProt
- P30120
Antigène
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