WSS1 (AA 1-269) anticorps (Biotin)

N° du produit ABIN7179221

Cet anticorps Lapin Polyclonal détecte spécifiquement WSS1 dans ELISA. Il présente une réactivité avec des échantillons de Saccharomyces cerevisiae.

Aperçu rapide pour WSS1 (AA 1-269) anticorps (Biotin) (ABIN7179221)

Antigène: WSS1

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: ELISA

Détail du produit

Épitope: AA 1-269

Fonction: WSS1 Antibody, Biotin conjugated

Réactivité croisée: Saccharomyces cerevisiae

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Saccharomyces cerevisiae DNA-dependent metalloprotease WSS1 protein (1-269AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: WSS1

Sujet:

Background: Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. Involved in the repair of toxic DNA-protein cross-links (DPCs) such as covalently trapped topoisomerase 1 (TOP1) adducts on DNA lesions or DPCs induced by reactive compounds such as formaldehyde. Involved in DNA damage response and processing of stalled or collapsed replication forks by removing the covalently trapped TOP1 from chromatin. DPC proteolysis enables the repair of the lesions via downstream DNA repair pathways. May be recruited to DPCs via the SUMOylation of substrate proteins at damaged DNA sites.

Aliases: WSS1 antibody, YHR134WDNA-dependent metalloprotease WSS1 antibody, EC 3.4.24.- antibody, DNA damage response protein WSS1 antibody, SUMO-dependent isopeptidase WSS1 antibody, Weak suppressor of SMT3 protein 1 antibody

UniProt: P38838