SRI anticorps (AA 32-116)

N° du produit ABIN7179479

Détail du produit anti-SRI anticorps

Antigène: SRI (Sorcin (SRI))

Épitope: AA 32-116

Reactivité: Staphylococcus aureus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRI est non-conjugé

Application: ELISA

Réactivité croisée: Staphylococcus aureus

Purification: >95%, Protein G purified

Immunogène: Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SRI

Antigène: SRI (Sorcin (SRI))

Autre désignation: scn (SRI Produits)

Synonymes: anticorps zgc:64070, anticorps sri, anticorps SRI, anticorps CP-22, anticorps CP22, anticorps SCN, anticorps V19, anticorps 2210417O06Rik, anticorps 2900070H08Rik, anticorps Sor, anticorps sorcin, anticorps Sorcin, anticorps sorcin L homeolog, anticorps sorcin S homeolog, anticorps SRI, anticorps sri, anticorps EDI_060410, anticorps EDI_160670, anticorps EDI_002860, anticorps EDI_076560, anticorps CpipJ_CPIJ004933, anticorps CpipJ_CPIJ008581, anticorps Tsp_05707, anticorps sri.L, anticorps sri.S, anticorps Sri

Sujet:

Background: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.

Aliases: scn antibody, SA1754 antibody, Staphylococcal complement inhibitor antibody, SCIN antibody

UniProt: Q99SU9

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity