HSP90AB1 anticorps (Ser254)

N° du produit ABIN7180024

Cet anticorps anti-HSP90AB1 Polyclonal Lapin (ABIN7180024) détecte spécifiquement HSP90AB1 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HSP90AB1 anticorps (Ser254) (ABIN7180024)

Antigène: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSP90AB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-HSP90AB1 anticorps

Épitope: Ser254

Fonction: HSP90AB1 (Ab-254) Antibody

Réactivité croisée: Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from Human HSP90B around the phosphorylation site of serine 254 (V-G-S(p)-D-E).

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HSP90AB1

Antigène: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Autre désignation: HSP90AB1

Sujet:

Background: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Lothar Goretzki, AACR Meeting Abstracts, Apr 2006, 2006: 468.
Jean-Fran?ois Louvion, Mol. Biol. Cell, Nov 1998, 9: 3071.
Angelika Lueking, Mol. Cell. Proteomics, Dec 2003, 2: 1342.
Jason Fontana Circ, Res., May 2002, 90: 866.

Aliases: 90 kda heat shock protein beta HSP90 beta antibody, D6S182 antibody, FLJ26984 antibody, Heat shock 84 kDa antibody, Heat shock 90kD protein 1, beta antibody, Heat shock 90 kDa protein 1 beta antibody, Heat shock protein 90 alpha family class B member 1 antibody, Heat shock protein 90 kDa antibody, Heat shock protein 90 kDa alpha (cytosolic) class B member 1 antibody, Heat shock protein 90 kDa alpha family class B member 1 antibody, Heat shock protein beta antibody, Heat shock protein HSP 90 beta antibody, Heat shock protein HSP 90-beta antibody, HS90B_HUMAN antibody, HSP 84 antibody, HSP 90 antibody, HSP 90 b antibody, HSP 90b antibody, HSP84 antibody, HSP90 BETA antibody, hsp90ab1 antibody, HSP90B antibody, HSPC2 antibody, HSPCB antibody

UniProt: P08238

Pathways: Regulation of Cell Size