AKR1A1 anticorps (C-Term)

N° du produit ABIN7180116

L’anticorps Lapin Polyclonal anti-AKR1A1 a été validé pour WB et ELISA. Il convient pour détecter AKR1A1 dans des échantillons de Humain.

Aperçu rapide pour AKR1A1 anticorps (C-Term) (ABIN7180116)

Antigène: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1A1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-AKR1A1 anticorps

Épitope: C-Term

Réactivité croisée: Humain, Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human AKR1A1.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur AKR1A1

Antigène: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Autre désignation: AKR1A1

Sujet:

Background: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

Bohren K.M., J. Biol. Chem. 264:9547-9551(1989).
Fujii J., Cytogenet. Cell Genet. 84:230-232(1999).
Barski O.A., Genomics 60:188-198(1999).

Aliases: AK1A1_HUMAN antibody, Akr1a1 antibody, Alcohol dehydrogenase [NADP+] antibody, Alcohol dehydrogenase antibody, Aldehyde reductase antibody, Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody, Aldo-keto reductase family 1 member A1 antibody, ALDR1 antibody, ALR antibody, ARM antibody, DD3 antibody, MGC12529 antibody, MGC1380 antibody

UniProt: P14550

Pathways: Monocarboxylic Acid Catabolic Process