CDCA2 anticorps (C-Term)
Aperçu rapide pour CDCA2 anticorps (C-Term) (ABIN7180137)
Antigène
Voir toutes CDCA2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Humain
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from C-terminal of Human CDCA2.
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Isotype
- IgG
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Indications d'application
- WB:1:500-1:3000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDCA2 (Cell Division Cycle Associated 2 (CDCA2))
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Autre désignation
- CDCA2
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Sujet
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Background: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
Walker M.G., Curr. Cancer Drug Targets 1:73-83(2001).
Ota T., . Genet. 36:40-45(2004).
Olsen J.V., Cell 127:635-648(2006).Aliases: CDCA2Cell division cycle-associated protein 2 antibody, Recruits PP1 onto mitotic chromatin at anaphase protein antibody, Repo-Man antibody
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UniProt
- Q69YH5
Antigène
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