MBD3 anticorps (C-Term)
Aperçu rapide pour MBD3 anticorps (C-Term) (ABIN7180199)
Antigène
Voir toutes MBD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Humain, Souris
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from C-terminal of Human MBD3.
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Isotype
- IgG
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Indications d'application
- WB:1:500-1:3000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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Autre désignation
- MBD3
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Sujet
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Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases.
Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998).
Grimwood J., Nature 428:529-535(2004).
Tatematsu K., Genes Cells 5:677-688(2000).Aliases: AI181826 antibody, AU019209 antibody, MBD 3 antibody, Mbd3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding domain protein 3 antibody, Methyl CpG binding protein MBD3 antibody, Methyl-CpG-binding domain protein 3 antibody, Methyl-CpG-binding protein MBD3 antibody
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UniProt
- O95983
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Pathways
- Chromatin Binding
Antigène
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