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MBD3 anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement MBD3 dans WB et ELISA. Il présente une réactivité envers Humain.
N° du produit ABIN7180199

Aperçu rapide pour MBD3 anticorps (C-Term) (ABIN7180199)

Antigène

Voir toutes MBD3 Anticorps
MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Reactivité

  • 66
  • 30
  • 17
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 56
  • 8
  • 2
Lapin

Clonalité

  • 51
  • 15
Polyclonal

Conjugué

  • 43
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp MBD3 est non-conjugé

Application

  • 42
  • 24
  • 12
  • 8
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • Épitope

    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

     Réactivité croisée

    Humain, Souris

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogène

    Synthesized peptide derived from C-terminal of Human MBD3.

    Isotype

    IgG
  • Indications d'application

    WB:1:500-1:3000,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène

    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

    Autre désignation

    MBD3

    Sujet

    Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases.

    Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998).
    Grimwood J., Nature 428:529-535(2004).
    Tatematsu K., Genes Cells 5:677-688(2000).

    Aliases: AI181826 antibody, AU019209 antibody, MBD 3 antibody, Mbd3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding domain protein 3 antibody, Methyl CpG binding protein MBD3 antibody, Methyl-CpG-binding domain protein 3 antibody, Methyl-CpG-binding protein MBD3 antibody

    UniProt

    O95983

    Pathways

    Chromatin Binding
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