Thrombomodulin anticorps (C-Term)

N° du produit ABIN7180265

Cet anticorps Lapin Polyclonal détecte spécifiquement Thrombomodulin dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Thrombomodulin anticorps (C-Term) (ABIN7180265)

Antigène: Thrombomodulin (THBD)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thrombomodulin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Thrombomodulin anticorps

Épitope: C-Term

Fonction: THBD Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from C-terminal of Human THBD.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Thrombomodulin

Antigène: Thrombomodulin (THBD)

Autre désignation: THBD

Sujet:

Background: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Suzuki K., EMBO J. 6:1891-1897(1987).
Wen D., Biochemistry 26:4350-4357(1987). Jackman R.W., Proc. Natl. Acad. Sci. U.S.A. 84:6425-6429(1987).

Aliases: AHUS 6 antibody, AHUS6 antibody, BDCA 3 antibody, BDCA3 antibody, CD 141 antibody, CD141 antibody, CD141 antigen antibody, Fetomodulin antibody, Thbd antibody, THPH12 antibody, THRM antibody, Thrombomodulin antibody, TM antibody, TRBM_HUMAN antibody

UniProt: P07204