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beta Synuclein anticorps

SNCB Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7182802
  • Antigène Voir toutes beta Synuclein (SNCB) Anticorps
    beta Synuclein (SNCB) (Synuclein, beta (SNCB))
    Reactivité
    • 50
    • 32
    • 32
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 57
    • 6
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 62
    • 4
    Polyclonal
    Conjugué
    • 31
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp beta Synuclein est non-conjugé
    Application
    • 36
    • 27
    • 25
    • 14
    • 14
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    Synthesized peptide derived from Human Synuclein beta antibody.
    Isotype
    IgG
  • Indications d'application
    WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    beta Synuclein (SNCB) (Synuclein, beta (SNCB))
    Autre désignation
    SNCB (SNCB Produits)
    Synonymes
    anticorps AI838531, anticorps betaSYN, anticorps zgc:66343, anticorps sncb, anticorps MGC75784, anticorps LOC619281, anticorps SNCB, anticorps syub, anticorps synuclein beta, anticorps synuclein, beta, anticorps synuclein beta L homeolog, anticorps Beta-synuclein, anticorps SNCB, anticorps Sncb, anticorps sncb, anticorps sncb.L, anticorps syub
    Sujet

    Background: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

    Yuxin Fan, Hum. Mol. Genet., Oct 2006, 15: 3002 - 3011.
    Makoto Hashimoto, J. Biol. Chem., May 2004, 279: 23622 - 23629.
    Cristine Alves da Costa, J. Biol. Chem., Sep 2003, 278: 37330 - 37335.
    Heather Snyder, J. Biol. Chem., Mar 2005, 280: 7562 - 7569.

    Aliases: 14 kDa brain-specific protein antibody, Beta-synuclein antibody, Phosphoneuroprotein 14 antibody, PNP14 antibody, Sncb antibody, Synuclein beta antibody, SYUB_HUMAN antibody

    UniProt
    Q16143
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