DCK anticorps (AA 181-260)
Aperçu rapide pour DCK anticorps (AA 181-260) (ABIN714176)
Antigène
Voir toutes DCK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 181-260
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Fonction
- DCK Polyclonal Antibody
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Homologie
- Human,Mouse,Rat,Pig,Horse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human DCK
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- DCK (Deoxycytidine Kinase (DCK))
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Autre désignation
- DCK
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Sujet
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Synonyms: DCK, dCK, DCK protein, DCK_HUMAN, Deoxycytidine kinase, EC 2.7.1, EC 2.7.1.74, MGC117410, MGC138632, OTTHUMP00000219118, OTTHUMP00000219119.
Background: Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.
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ID gène
- 1633
Antigène
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