SENP3 anticorps

N° du produit ABIN7184127

L’anticorps Lapin Polyclonal anti-SENP3 a été validé pour WB, ELISA et IHC. Il convient pour détecter SENP3 dans des échantillons de Humain.

Aperçu rapide pour SENP3 anticorps (ABIN7184127)

Antigène: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SENP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SENP3 anticorps

Fonction: SENP3 Antibody

Réactivité croisée: Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from Internal of Human SENP3.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SENP3

Antigène: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Autre désignation: SENP3

Sujet:

Background: Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Yeh E.T.H., Gene 248:1-14(2000).
Choi S.J., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Wiemann S., Genome Res. 11:422-435(2001).

Aliases: SENP3 antibody, SENP3_HUMAN antibody, Sentrin / SUMO specific protease 3 antibody, Sentrin specific protease 3 antibody, Sentrin-specific protease 3 antibody, Sentrin/SUMO-specific protease SENP3 antibody, SMT3IP1 antibody, SSP3 antibody, SUMO 1 specific protease 3 antibody, SUMO-1-specific protease 3 antibody, SUMO1 specific protease 3 antibody, SUMO1/sentrin/SMT3 specific peptidase 3 antibody, SUSP3 antibody

UniProt: Q9H4L4