MATK anticorps (AA 411-507) (Cy5)

N° du produit ABIN714210

Cet anticorps anti-MATK est un anticorps Lapin Polyclonal détectant MATK dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour MATK anticorps (AA 411-507) (Cy5) (ABIN714210)

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MATK est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MATK anticorps (Cy5)

Épitope: AA 411-507

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MATK

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MATK

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Autre désignation: MATK

Sujet:

Synonyms: CHK, Csk homologous kinase, Csk type protein tyrosine kinase, CTK, Hematopoietic consensus tyrosine lacking kinase, HHYLTK, Hydroxyaryl protein kinase, HYL, HYL tyrosine kinase, HYLTK, Leukocyte carboxyl terminal src kinase related, Lsk, Megakaryocyte associated tyrosine kinase, Megakaryocyte associated tyrosine protein kinase, Protein kinase HYL, Tyrosine kinase MATK, Tyrosine protein kinase CTK, Tyrosylprotein kinase, MATK_HUMAN.

Background: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

ID gène: 4145