CNOT7 anticorps (N-Term)

N° du produit ABIN7184433

L’anticorps Lapin Polyclonal anti-CNOT7 a été validé pour WB et ELISA. Il convient pour détecter CNOT7 dans des échantillons de Humain.

Aperçu rapide pour CNOT7 anticorps (N-Term) (ABIN7184433)

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT7 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CNOT7 anticorps

Épitope: N-Term

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from N-terminal of Human CNOT7.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CNOT7

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Autre désignation: CNOT7

Sujet:

Background: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

Bogdan J.A., Biochem. J. 336:471-481(1998).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: BTG1 binding factor 1 antibody, BTG1-binding factor 1 antibody, CAF 1 antibody, CAF-1 antibody, CAF1 antibody, Carbon catabolite repressor protein (CCR4) associative factor 1 antibody, CCR4 associated factor 1 antibody, CCR4 NOT transcription complex subunit 7 antibody, CCR4-associated factor 1 antibody, CCR4-NOT transcription complex subunit 7 antibody, CNOT 7 antibody, Cnot7 antibody, CNOT7_HUMAN antibody, hCAF 1 antibody, hCAF1 antibody

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization