HCFC1 anticorps (N-Term)

N° du produit ABIN7184458

Cet anticorps anti-HCFC1 est un anticorps Lapin Polyclonal détectant HCFC1 dans IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour HCFC1 anticorps (N-Term) (ABIN7184458)

Antigène: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCFC1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-HCFC1 anticorps

Épitope: N-Term

Réactivité croisée: Humain, Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from N-terminal of Human HCFC1.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HCFC1

Antigène: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Autre désignation: HCFC1

Sujet:

Background: Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2, represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case of human herpes simplex virus (HSV) infection, HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes.

Wilson A.C., Cell 74:115-125(1993).
Kristie T.M., J. Biol. Chem. 270:4387-4394(1995).
Ross M.T., Nature 434:325-337(2005).

Aliases: C1 factor antibody, CFF antibody, HCF 1 antibody, HCF antibody, HCF C-terminal chain 6 antibody, HCF-1 antibody, HCF1 antibody, Hcfc1 antibody, HCFC1_HUMAN antibody, HFC1 antibody, Host cell factor 1 antibody, Host cell factor antibody, Host cell factor C1 (VP16 accessory protein) antibody, Host cell factor C1 antibody, MGC70925 antibody, MRX3 antibody, VCAF antibody, VP16 accessory protein antibody

UniProt: P51610