KLHL3 anticorps (N-Term)

N° du produit ABIN7184471

Cet anticorps Lapin Polyclonal détecte spécifiquement KLHL3 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour KLHL3 anticorps (N-Term) (ABIN7184471)

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-KLHL3 anticorps

Épitope: N-Term

Fonction: KLHL3 Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from N-terminal of Human KLHL3.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KLHL3

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Autre désignation: KLHL3

Sujet:

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.

Lai F., Genomics 66:65-75(2000).
Hirosawa M., DNA Res. 6:329-336(1999).
Ota T., Nat. Genet. 36:40-45(2004).

Aliases: KLHL3 antibody, KIAA1129 antibody, Kelch-like protein 3 antibody

UniProt: Q9UH77