CDH23 anticorps (C-Term)

N° du produit ABIN7189385

Détail du produit anti-CDH23 anticorps

Antigène: CDH23 (Cadherin 23 (CDH23))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDH23 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen Affinity Purified

Immunogène: Synthetic peptide corresponding to residues near the C terminal of Human pan-cadherin

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in pH 7.3 PBS, 0.05 % Sodium azide, 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CDH23

Antigène: CDH23 (Cadherin 23 (CDH23))

Autre désignation: CDH23 (CDH23 Produits)

Synonymes: anticorps 4930542A03Rik, anticorps USH1D, anticorps ahl, anticorps ahl1, anticorps bob, anticorps bus, anticorps mdfw, anticorps nmf112, anticorps nmf181, anticorps nmf252, anticorps sals, anticorps v, anticorps CDHR23, anticorps W, anticorps cadherin 23 (otocadherin), anticorps cadherin related 23, anticorps cadherin-related 23, anticorps Cdh23, anticorps CDH23

Sujet:

Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Aliases: CDH23 antibody, KIAA1774 antibody, KIAA1812 antibody, UNQ1894/PRO4340Cadherin-23 antibody, Otocadherin antibody

UniProt: Q9H251

Pathways: Sensory Perception of Sound