AD7C-NTP anticorps
Aperçu rapide pour AD7C-NTP anticorps (ABIN7189642)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- AD7C-NTP Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Synthetic peptide of Human AD7C-NTP
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- AD7C-NTP
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Sujet
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Background: The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.
Aliases: Neuronal thread protein AD7c-NTP
Antigène
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