ANKRD28 anticorps
Aperçu rapide pour ANKRD28 anticorps (ABIN7189809)
Antigène
Voir toutes ANKRD28 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- ANKRD28 Antibody
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Réactivité croisée
- Souris
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Purification
- Antigen affinity purification
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Immunogène
- Synthetic peptide of Human ANKRD28
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ANKRD28 (Ankyrin Repeat Domain 28 (ANKRD28))
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Autre désignation
- ANKRD28
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Sujet
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Background: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.
Aliases: ANKRD28 antibody, KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody, PP6-ARS-A antibody, Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody, Ankyrin repeat domain-containing protein 28 antibody, Phosphatase interactor targeting protein hnRNP K antibody, PITK antibody
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UniProt
- O15084
Antigène
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