Bestrophin 1 anticorps

N° du produit ABIN7189978

Cet anticorps Lapin Polyclonal détecte spécifiquement Bestrophin 1 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Bestrophin 1 anticorps (ABIN7189978)

Antigène: Bestrophin 1 (BEST1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Bestrophin 1 anticorps

Fonction: BEST1 Antibody

Réactivité croisée: Souris

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human BEST1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: BEST1

Sujet:

Background: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Aliases: ARB antibody, BEST 1 antibody, BEST antibody, Best disease antibody, Best macular dystrophy antibody, BEST1 antibody, BEST1_HUMAN antibody, Best1V1Delta2 antibody, Bestrophin 1 antibody, Bestrophin-1 antibody, Bestrophin1 antibody, BMD antibody, mBest1 antibody, RP50 antibody, TU15B antibody, Vitelliform macular dystrophy 2 antibody, Vitelliform macular dystrophy antibody, Vitelliform macular dystrophy protein 2 antibody, VMD 2 antibody, VMD2 antibody

UniProt: O76090