CHRDL2 anticorps

N° du produit ABIN7190246

L’anticorps Lapin Polyclonal anti-CHRDL2 a été validé pour WB, IHC et ELISA. Il convient pour détecter CHRDL2 dans des échantillons de Humain.

Aperçu rapide pour CHRDL2 anticorps (ABIN7190246)

Antigène: CHRDL2 (Chordin-Like 2 (CHRDL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRDL2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CHRDL2 anticorps

Fonction: CHRDL2 Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human CHRDL2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CHRDL2

Antigène: CHRDL2 (Chordin-Like 2 (CHRDL2))

Autre désignation: CHRDL2

Sujet:

Background: CHRDL2 (chordin-related protein 2), also known as BNF1 (breast tumor novel factor 1) or CHL2 (chordin-like 2), is a 429 amino acid protein that belongs to the chordin family of proteins. CHRDL2 contains three VWFC (von Willebrand Factor type C) domains and is predominantly expressed in uterus and moderately expressed in prostate, liver, ovary, heart and testis. Due to alternative splicing events, CHRDL2 exists as five isoforms, namely isoform I, isoform II, isoform VII, isoform VIII and isoform IX. Two of these isoforms are secreted, while the other three localize to the cytoplasm. Functioning as a BMP-binding inhibitor, CHRDL2 directly interacts with BMPs and blocks their binding to BMP receptors, thereby inhibiting BMP activity. In breast, lung and colon tumors, CHRDL2 expression is upregulated, suggesting a possible role in tumorigenesis.

Aliases: BNF-1 antibody, BNF1 antibody, Breast tumor novel factor 1 antibody, CHL2 antibody, chordin like 2 antibody, Chordin like protein 2 precursor antibody, Chordin related protein 2 antibody, Chordin-like protein 2 antibody, Chordin-related protein 2 antibody, Chrdl2 antibody, CRDL2_HUMAN antibody, DKFZp586N2124 antibody, FKSG37 antibody

UniProt: Q6WN34