Claudin 19 anticorps

N° du produit ABIN7190275

Détail du produit anti-Claudin 19 anticorps

Antigène: Claudin 19 (CLDN19)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 19 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human CLDN19

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Claudin 19

Antigène: Claudin 19 (CLDN19)

Autre désignation: CLDN19 (CLDN19 Produits)

Synonymes: anticorps HOMG5, anticorps claudin-19, anticorps zgc:112141, anticorps claudin 19, anticorps claudin 19 S homeolog, anticorps CLDN19, anticorps Cldn19, anticorps cldn19.S, anticorps cldn19

Sujet:

Background: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Aliases: CLDN19Claudin-19 antibody

UniProt: Q8N6F1

Pathways: Cell-Cell Junction Organization, Hepatitis C