FAT4 anticorps
Aperçu rapide pour FAT4 anticorps (ABIN7190632)
Antigène
Voir toutes FAT4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- FAT4 Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Synthetic peptide of Human FAT4
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
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Autre désignation
- FAT4
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Sujet
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Background: FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by γ secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.
Aliases: Cadherin family member 14 antibody, Cadherin related family member 11 antibody, CDHF14 antibody, CDHR11 antibody, FAT atypical cadherin 4 antibody, FAT J antibody, FAT tumor suppressor homolog 4 antibody, Fat-like cadherin protein FAT-J antibody, FAT4 antibody, FAT4_HUMAN antibody, FATJ antibody, hFat4 antibody, HKLLS2 antibody, Nbla00548 antibody, Protocadherin Fat 4 antibody, Putative protein product of Nbla00548 antibody, VMLDS2 antibody
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UniProt
- Q6V0I7
Antigène
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