MED14 anticorps

N° du produit ABIN7191443

Détail du produit anti-MED14 anticorps

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED14 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human MED14

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MED14

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Autre désignation: MED14 (MED14 Produits)

Synonymes: anticorps CG12031, anticorps Dmel\\CG12031, anticorps Med14, anticorps Trap170, anticorps dTRAP170, anticorps p160, anticorps EXLM1, anticorps crsp150, anticorps crsp2, anticorps trap170, anticorps wu:fd21c05, anticorps wu:fk28h11, anticorps CRSP2, anticorps NV18605, anticorps CRSP150, anticorps CSRP, anticorps CXorf4, anticorps DRIP150, anticorps RGR1, anticorps TRAP170, anticorps 9930001L01Rik, anticorps AU041628, anticorps Crsp2, anticorps ENSMUSG00000073278, anticorps Gm641, anticorps ORF1, anticorps RGD1560170, anticorps Mediator complex subunit 14, anticorps mediator complex subunit 14, anticorps mediator of RNA polymerase II transcription subunit 14, anticorps transcriptional regulation, anticorps MED14, anticorps med14, anticorps LOC100113592, anticorps Med14, anticorps RGR1

Sujet:

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Aliases: Activator-recruited cofactor 150 kDa component antibody, ARC150 antibody, Cofactor required for Sp1 transcriptional activation subunit 2 antibody, CRSP complex subunit 2 antibody, DRIP150 antibody, EXLM1 antibody, hRGR1 antibody, MED14 antibody, MED14_HUMAN antibody, Mediator complex subunit 14 antibody, Mediator of RNA polymerase II transcription subunit 14 antibody, RGR1 antibody, RGR1 homolog antibody, Thyroid hormone receptor-associated protein complex 170 kDa component antibody, Transcriptional coactivator CRSP150 antibody, Trap170 antibody, Vitamin D3 receptor-interacting protein complex 150 kDa component antibody

UniProt: O60244

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha