SLC8A2 anticorps

N° du produit ABIN7192526

L’anticorps Lapin Polyclonal anti-SLC8A2 a été validé pour ELISA et IHC. Il convient pour détecter SLC8A2 dans des échantillons de Humain.

Aperçu rapide pour SLC8A2 anticorps (ABIN7192526)

Antigène: SLC8A2 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 2 (SLC8A2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC8A2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SLC8A2 anticorps

Fonction: SLC8A2 Antibody

Réactivité croisée: Rat

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human SLC8A2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SLC8A2

Antigène: SLC8A2 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 2 (SLC8A2))

Autre désignation: SLC8A2

Sujet:

Background: Sodium/calcium exchanger proteins are integral membrane proteins primarily seen in cardiac cells. In cardiac myocytes, the concentration of Ca2+ alternates between low levels during relaxation and high levels during contraction. The Na+/Ca2+ exchanger 1 (NCX1) protein mediates Ca2+ extrusion from cardiac cells during relaxation. Four NCX1 isoforms (NCX1.1, NCX1.3, NCX1.7, and NCX1.10) result from alternate splicing. NCX1 mRNA is present at high levels in the heart, with lower levels present in the brain. NCX2 is most abundantly expressed in brain, in contrast the the broader distribution of NCX1, which is also expressed in heart, kidney, lung, smooth and skeletal muscle. The difference in expression for the transporter subtypes is believed to reflect differences in their functional roles. Regulation mechanisms for these exchanger proteins have not been fully characterized.

Aliases: SLC8A2 antibody, KIAA1087 antibody, NCX2 antibody, Sodium/calcium exchanger 2 antibody, Na(+)/Ca(2+)-exchange protein 2 antibody, Solute carrier family 8 member 2 antibody

UniProt: Q9UPR5