SPAG1 anticorps

N° du produit ABIN7192612

Cet anticorps Lapin Polyclonal détecte spécifiquement SPAG1 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour SPAG1 anticorps (ABIN7192612)

Antigène: SPAG1 (Sperm Associated Antigen 1 (SPAG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SPAG1 anticorps

Réactivité croisée: Humain

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human SPAG1

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SPAG1

Antigène: SPAG1 (Sperm Associated Antigen 1 (SPAG1))

Autre désignation: SPAG1

Sujet:

Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.

Aliases: SPAG1 antibody, Sperm-associated antigen 1 antibody, HSD-3.8 antibody, Infertility-related sperm protein Spag-1 antibody

UniProt: Q07617